Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.81 |
| ▸ | MEN1 | O00255 | 7/20 | 0.81 |
| ▸ | MAPT | P10636 | 6/20 | 0.81 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.79 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.79 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.79 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | XBP1 | P17861 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | GLA | P06280 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | PRNP | P04156 | 1/20 | 0.61 |
| ▸ | PPARG | P37231 | 1/20 | 0.61 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22542990 | 0.90 | CYP2C9 (0.73) | KMT2AMEN1MAPTCYP2C9CYP3A4 | |
| SCHEMBL22542971 | 0.90 | KMT2A (0.81) | KMT2AMEN1MAPTCYP2C9CYP3A4 | |
| SCHEMBL22542851 | 0.88 | KMT2A (0.63) | KMT2AMEN1MAPTCYP2C9CYP3A4 | |
| SCHEMBL22543378 | 0.88 | KMT2A (0.79) | KMT2AMEN1MAPTCYP2C9CYP3A4 | |
| SCHEMBL22542999 | 0.83 | KMT2A (0.58) | KMT2AMEN1MAPTCYP2C9CYP3A4 | |
| SCHEMBL7821284 | 0.82 | KMT2A (0.81) | KMT2AMEN1MAPTCYP2C9CYP3A4 | |
| SCHEMBL22542846 | 0.79 | CYP2C9 (0.74) | KMT2AMEN1MAPTCYP2C9CYP3A4 | |
| SCHEMBL22543115 | 0.78 | CYP2C9 (0.65) | KMT2AMEN1MAPTCYP2C9CYP3A4 | |
| SCHEMBL22543110 | 0.78 | CYP2C9 (0.77) | KMT2AMEN1MAPTCYP2C9CYP3A4 | |
| SCHEMBL22543067 | 0.78 | CYP2C9 (0.73) | KMT2AMEN1MAPTCYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200323960-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING ONCOSTATIN M (OSM) ANTAGONIST DERIVATIVES AND METHODS OF USE | BOISE STATE UNIVERSITY | 2020-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200323960-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING ONCOSTATIN M (OSM) ANTAGONIST DERIVATIVES AND METHODS OF USE | OGFR, OGFRL1, ELAVL1 | KMT2A 1580/4885MEN1 1818/4885MAPT 2358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.