Sugi Predict

Sugi Predict / Targets / OGFR

OGFR

Opioid growth factor receptor · Q9NZT2 · OGFR on Sugi Atlas →

0 patent compounds predicted against OGFR, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to OGFR by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Treatment of Chronic Pain From Osteoarthritis PHASE4WITHDRAWN
Colonic Motor Patterns in Healthy Volunteers PHASE4COMPLETED
Effects of Tapentadol Versus Oxycodone After Hysterectomy. PHASE4COMPLETED
Real World Study of Oxycodone/Naloxone Sustained-Release Tablets (Mimeixin) for Patients With Severe Cancer Pain PHASE4NOT_YET_RECRUITING
Effect of Magnesium Sulfate Bolus on Intraoperative Neuromonitoring PHASE4RECRUITING
Prospective Study About Clinical and Pharmacogenetic Safety of Opioid Use for Chronic Pain PHASE4SUSPENDED
Methylnaltrexone vs Naloxegol in the Treatment of Opioid-Induced Constipation PHASE4COMPLETED
Topical Morphine for Analgesia in Patients With Skin Grafts PHASE3WITHDRAWN
Evaluating the Efficacy of Intranasal Oxytocin Among Individuals With Persistent Pain PHASE2/PHASE3COMPLETED
Assessment of Long-term Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation PHASE3COMPLETED
Opioid Growth Factor in Treating Patients With Advanced Pancreatic Cancer That Cannot Be Removed By Surgery PHASE2COMPLETED
Effect of Locally Administered Morphine and Bupivicaine on Acute and Chronic Postmastectomy Pain PHASE2COMPLETED
A Series of Pilot Studies to Evaluate the haemoDynamic and mEtabolic Effects oF apelIn aNd rElaxin PHASE2UNKNOWN
Acute and Short-term Effects of Cannabidiol Admin on Cue-induced Craving in Drug-abstinent Heroin Dependent Humans PHASE2COMPLETED
Acute and Short-term Effects of CBD on Cue-induced Craving in Drug-abstinent Heroin-dependent Humans PHASE2COMPLETED
Safety and Efficacy of the PAINLESS Nerve Growth Factor CHF6467 in Optic Pathway Glioma (OPG) PHASE2ACTIVE_NOT_RECRUITING
Feasibility Study of Oral Naloxone for Treatment of Methadone-induced Constipation PHASE2COMPLETED
Treatment of Unresectable Hepatocellular Cancer With Opioid Growth Factor PHASE1COMPLETED
Study to Test the Safety and Efficacy of Cannabidiol as a Treatment Intervention for Opioid Relapse PHASE1COMPLETED
Pharmacokinetics of Intravenous and Intranasal Formulations of Naloxone in Healthy Volunteers. PHASE1COMPLETED
Effect of Intraperitoneal Bupivacaine with Dexmedotomidine or Fentanyl for Post-Operative Analgesia Following Laparoscopy in Pediatric Patients nanNOT_YET_RECRUITING
Multicenter Perioperative Opioid Pharmacogenetic Study nanCOMPLETED
Precision Medicine in Anesthesia nanWITHDRAWN
Effect of Fentanyl on Main Opioid Receptor (OPRM1) on Human Granulosa Cells. nanUNKNOWN
Intermountain Healthcare's Enhanced Recovery Protocol for Colon Surgery With and Without Alvimopan Use nanCOMPLETED
Duration of Analgesia in Bier Block for Patients Undergoing Hand Surgery nanUNKNOWN
Determining Genetic Biomarkers Predictive of the Development of Prescription Opioid Addiction nanUNKNOWN
Reflexology Socks and Opioid-induced Constipation nanCOMPLETED
Nalbuphine Versus Fentanyl As Additives To Bupivacaine In Spinal Anaesthesia For Internal FixationI Of Tibia nanCOMPLETED
MOR-1 Expression in Colorectal Cancer and Disease-free Survival Relationship. Five-year Follow-up. nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a OGFR binder may also engage these)

ProteinNameSimilarity
Q99PG2 — 0.996 Q99PG2 →
Q9QXY4 — 0.993 Q9QXY4 →
Q96JP2 — 0.987 Q96JP2 →
Q8BZW2 — 0.986 Q8BZW2 →
A0A8I3PMN2 — 0.986 A0A8I3PMN2 →
P17564 — 0.984 P17564 →
MSL1 Male-specific lethal 1 homolog 0.984 landscape →
Q8BG26 — 0.984 Q8BG26 →
Q7Z6P3 — 0.984 Q7Z6P3 →
Q76N89 — 0.984 Q76N89 →
P49919 — 0.984 P49919 →
Q9H7P9 — 0.984 Q9H7P9 →
Q9Y6A5 — 0.983 Q9Y6A5 →
Q9JJ89 — 0.983 Q9JJ89 →
LMTK3 Serine/threonine-protein kinase LMTK3 0.983 landscape →
Q8BLR5 — 0.983 Q8BLR5 →
Q8NDX1 — 0.983 Q8NDX1 →
O95201 — 0.983 O95201 →
Q9Y5B0 — 0.983 Q9Y5B0 →
Q8C1M2 — 0.982 Q8C1M2 →
Q8WUU4 — 0.982 Q8WUU4 →
Q8N1P7 — 0.982 Q8N1P7 →
Q9UDV7 — 0.982 Q9UDV7 →
Q80SU3 — 0.982 Q80SU3 →
Q9Y4B5 — 0.982 Q9Y4B5 →
Q2KI51 — 0.982 Q2KI51 →
O18805 — 0.982 O18805 →
Q7Z591 — 0.982 Q7Z591 →
Q9Z0E3 — 0.982 Q9Z0E3 →
Q8TBE0 — 0.982 Q8TBE0 →