Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 5/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PDE1A | P54750 | 1/20 | 0.41 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.41 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.41 |
| ▸ | NOX4 | Q9NPH5 | 3/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18326378 | 0.87 | GABRA5 (0.45) | GABRA5GABRA1BRD4KDM4EGLA | |
| SCHEMBL29732326 | 0.87 | GABRA5 (0.45) | GABRA5GABRA1BRD4KDM4EGLA | |
| SCHEMBL20373464 | 0.82 | GABRA5 (0.43) | GABRA5GABRA1BRD4KDM4EGLA | |
| SCHEMBL18359585 | 0.80 | HTR2A (0.45) | GABRA5GABRA1KDM4EGLAALDH1A1 | |
| Odm-207 SCHEMBL16896828 | 0.79 | BRD4 (0.60) | GABRA5GABRA1BRD4 | |
| Odm-207 SCHEMBL29732197 | 0.79 | BRD4 (0.60) | GABRA5GABRA1BRD4 | |
| SCHEMBL20373279 | 0.79 | PDE1A (0.40) | GABRA5GABRA1BRD4KDM4EALDH1A1 | |
| SCHEMBL16896890 | 0.74 | HTR2A (0.43) | GABRA5GABRA1BRD4KDM4EGLA | |
| SCHEMBL18359489 | 0.74 | KDM4E (0.43) | GABRA5GABRA1KDM4EALDH1A1RAB9A | |
| SCHEMBL20547340 | 0.74 | BRD4 (0.61) | GABRA5GABRA1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020208307-A1 | CRYSTALLINE FORM OF A BET-INHIBITOR AND MANUFACTURE THEREOF | ORION CORPORATION (FI) | 2020-10-15 | — | — | WO | disclosed |