Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | PHPT1 | Q9NRX4 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4962114 | 0.80 | LMNA (0.64) | ESR1ESR2KDM4EHDAC1APOBEC3A | |
| SCHEMBL17991076 | 0.80 | KMT2A (0.56) | ESR1ESR2HDAC1POLBSMN1; SMN2 | |
| SCHEMBL31627918 | 0.79 | HDAC1 (0.58) | ESR1ESR2KDM4EHDAC1SMN1; SMN2 | |
| SCHEMBL30388573 | 0.79 | HDAC1 (0.58) | ESR1ESR2KDM4EHDAC1POLB | |
| SCHEMBL16423991 | 0.79 | HDAC1 (0.58) | ESR1ESR2KDM4EHDAC1POLB | |
| SCHEMBL1108319 | 0.79 | ESR1 (0.44) | ESR1ESR2HDAC1POLBMEN1 | |
| SCHEMBL16424476 | 0.77 | HDAC1 (0.60) | ESR1ESR2KDM4EHDAC1SMN1; SMN2 | |
| SCHEMBL29838140 | 0.77 | HDAC1 (0.60) | ESR1ESR2KDM4EHDAC1SMN1; SMN2 | |
| SCHEMBL11940934 | 0.77 | KMT2A (0.62) | KDM4EPOLBSMN1; SMN2LMNAPDK2 | |
| SCHEMBL22550191 | 0.76 | LIG1 (0.38) | ESR1ESR2KDM4EPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10981865-B2 | Substituted or unsubstituted allyl group-containing maleimide compound, production method therefor, and composition and cured product using said compound | DIC CORPORATION (JP) | 2021-04-20 | — | — | US | disclosed |
| US-20200325101-A1 | SUBSTITUTED OR UNSUBSTITUTED ALLYL GROUP-CONTAINING MALEIMIDE COMPOUND, PRODUCTION METHOD THEREFOR, AND COMPOSITION AND CURED PRODUCT USING SAID COMPOUND | DIC CORPORATION (JP) | 2020-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10981865-B2 | Substituted or unsubstituted allyl group-containing maleimide compound, production method therefor, and composition and cured product using said compound | BMI1, WEE1, WEE2 | ESR1 200/4885ESR2 757/4885KDM4E 51/4885 |
| US-20200325101-A1 | SUBSTITUTED OR UNSUBSTITUTED ALLYL GROUP-CONTAINING MALEIMIDE COMPOUND, PRODUCTION METHOD THEREFOR, AND COMPOSITION AND CURED PRODUCT USING SAID COMPOUND | BMI1, WEE1, WEE2 | ESR1 200/4885ESR2 757/4885KDM4E 51/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.