Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 10/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.41 |
| ▸ | MAP3K6 | O95382 | 1/20 | 0.41 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20718135 | 1.00 | NOTUM (0.49) | NOTUMCTSKABL1MTORWNT3A | |
| SCHEMBL22550526 | 1.00 | NOTUM (0.49) | NOTUMCTSKABL1MTORWNT3A | |
| SCHEMBL22793399 | 0.88 | NOTUM (0.52) | NOTUMCTSKABL1MTORWNT3A | |
| SCHEMBL22550382 | 0.86 | NOTUM (0.50) | NOTUMCTSKABL1MTORWNT3A | |
| SCHEMBL20718421 | 0.86 | NOTUM (0.50) | NOTUMCTSKABL1MTORWNT3A | |
| SCHEMBL20718428 | 0.86 | NOTUM (0.50) | NOTUMCTSKABL1MTORWNT3A | |
| SCHEMBL9606798 | 0.85 | NOTUM (0.47) | NOTUMCTSKABL1MTORWNT3A | |
| SCHEMBL22550333 | 0.79 | ALDH1A1 (0.52) | CTSKKDM4EALDH1A1 | |
| SCHEMBL22550682 | 0.79 | ALDH1A1 (0.52) | CTSKKDM4EALDH1A1 | |
| SCHEMBL22550631 | 0.79 | ALDH1A1 (0.52) | CTSKKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200325177-A1 | METHODS OF MAKING STREPTOGRAMIN COMPOSITIONS AND THE USE THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2020-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200325177-A1 | METHODS OF MAKING STREPTOGRAMIN COMPOSITIONS AND THE USE THEREOF | PLG, LIPA, MB | NOTUM 648/4885CTSK 592/4885ABL1 2853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.