Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20718372 | 0.85 | SMN1; SMN2 (0.60) | SMN1; SMN2RAB9ANPC1HPGDCYP1A2 | |
| SCHEMBL20717850 | 0.85 | SMN1; SMN2 (0.60) | SMN1; SMN2RAB9ANPC1HPGDCYP1A2 | |
| SCHEMBL22550593 | 0.85 | SMN1; SMN2 (0.60) | SMN1; SMN2RAB9ANPC1HPGDCYP1A2 | |
| SCHEMBL22550553 | 0.84 | MEN1 (0.52) | SMN1; SMN2RAB9ANPC1HPGDL3MBTL1 | |
| SCHEMBL22550596 | 0.84 | NPC1 (0.56) | SMN1; SMN2RAB9ANPC1HPGDLMNA | |
| SCHEMBL19861792 | 0.82 | RAB9A (0.57) | SMN1; SMN2RAB9ANPC1HPGDCYP1A2 | |
| SCHEMBL21059104 | 0.80 | SMN1; SMN2 (0.65) | SMN1; SMN2RAB9ANPC1HPGDCYP1A2 | |
| SCHEMBL20718178 | 0.79 | SMN1; SMN2 (0.67) | SMN1; SMN2RAB9ANPC1HPGDCYP1A2 | |
| SCHEMBL21059190 | 0.79 | RAB9A (0.73) | SMN1; SMN2RAB9ANPC1HPGDCYP1A2 | |
| SCHEMBL22793106 | 0.77 | SMN1; SMN2 (0.57) | SMN1; SMN2RAB9ANPC1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200325177-A1 | METHODS OF MAKING STREPTOGRAMIN COMPOSITIONS AND THE USE THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2020-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200325177-A1 | METHODS OF MAKING STREPTOGRAMIN COMPOSITIONS AND THE USE THEREOF | PLG, LIPA, MB | SMN1; SMN2 3525/4885RAB9A 3115/4885NPC1 2832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.