Fructose

Fructose

SCHEMBL22551085

C(OCC1CO1)C1CO1.O=C(CO)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.38
CYP2C9 P11712 1/20 0.38
PDE4A P27815 1/20 0.34
ALDH1A1 P00352 3/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
LMNA P02545 2/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fructose SCHEMBL28228489 1.00 TSHR (0.38) TSHRCYP2C9PDE4AALDH1A1TP53
Fructose SCHEMBL1177854 1.00 TSHR (0.38) TSHRCYP2C9PDE4AALDH1A1TP53
Adonitol SCHEMBL20637061 0.83 TSHR (0.45) TSHRPDE4AALDH1A1TP53CYP3A4
Mannitol SCHEMBL26107249 0.83 LMNA (0.46) TSHRPDE4AALDH1A1TP53CYP3A4
Mannitol SCHEMBL28735254 0.83 LMNA (0.46) TSHRPDE4AALDH1A1TP53CYP3A4
Fructose SCHEMBL11269912 0.83 TDP1 (0.42) TSHRCYP2C9PDE4AALDH1A1LMNA
Fructose SCHEMBL26969226 0.80 CYP2C9 (0.47) TSHRCYP2C9PDE4ALMNAL3MBTL1
E968 SCHEMBL29164486 0.79 TSHR (0.48) TSHRALDH1A1TP53CYP3A4LMNA
E968 SCHEMBL11703391 0.79 TSHR (0.48) TSHRALDH1A1TP53CYP3A4LMNA
Tagatose SCHEMBL23827342 0.77 CYP2C9 (0.58) TSHRCYP2C9PDE4ALMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3724143-A1 INSULATION PRODUCT COMPRISING MINERAL FIBERS AND A BINDER SAINT-GOBAIN ISOVER (FR) 2020-10-21 EP disclosed