SCHEMBL22551597

SCHEMBL22551597

CC(C)(C)C(N)CCS(=O)(=O)O

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.39
SLC6A6 P31641 1/20 0.39
CYP2C19 P33261 1/20 0.39
BLM P54132 1/20 0.39
APP P05067 1/20 0.36
S1PR2 O95136 1/20 0.36
S1PR1 P21453 1/20 0.36
S1PR3 Q99500 1/20 0.36
PTGS1 P23219 1/20 0.33
PDE4A P27815 1/20 0.33
TP53 P04637 1/20 0.33
ENPEP Q07075 4/20 0.33
PMP22 Q01453 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23781788 0.87 APP (0.43) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL1792906 0.76 SLC22A6 (0.36) LMNASLC6A6CYP2C19BLMTP53
SCHEMBL6018860 0.76 SLC22A6 (0.36) LMNASLC6A6CYP2C19BLMTP53
SCHEMBL1234580 0.76 LMNA (0.37) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL22551551 0.76 LMNA (0.42) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL10001199 0.74 PMP22 (0.38) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL356494 0.73
SCHEMBL21623887 0.73
SCHEMBL5170445 0.72 S1PR2 (0.43) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL1977489 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110396165-B Ionically hydrophilicized polyisocyanates and antioxidants 科思创德国股份有限公司 2022-12-06 CN disclosed
CN-112041369-B Ionically hydrophilicized polyisocyanates, water content 科思创知识产权两合公司 2022-11-29 CN disclosed
CN-115066445-A Polyisocyanate formulations 科思创德国股份有限公司 2022-09-16 CN disclosed
CN-113651944-B Ionically hydrophilicized polyisocyanates having improved drying properties 科思创知识产权两合公司 2022-07-15 CN disclosed
CN-112062935-B Preparation method and application of odorless water-dispersible polyisocyanate 广东也乐新材料制造有限公司 2022-02-11 CN disclosed
CN-112566957-B Ionically hydrophilicized polyisocyanates having improved drying properties 科思创知识产权两合公司 2021-12-10 CN disclosed
CN-113651944-A Ionically hydrophilicized polyisocyanates having improved drying properties 科思创知识产权两合公司 2021-11-16 CN disclosed
EP-3875513-A1 IONICALLY HYDROPHILIZED POLYISOCYANATES AND RADICAL SCAVENGER AND/OR PEROXIDE DECOMPOSITION AGENT Covestro Intellectual Property GmbH & Co. KG (DE) 2021-09-08 EP disclosed
CN-112566957-A Ionically hydrophilicized polyisocyanates having improved drying properties 科思创知识产权两合公司 2021-03-26 CN disclosed
CN-112062935-A Preparation method and application of odorless water-dispersible polyisocyanate 广东也乐新材料制造有限公司 2020-12-11 CN disclosed
CN-112041369-A Ionically hydrophilicized polyisocyanates, water content 科思创知识产权两合公司 2020-12-04 CN disclosed
EP-3724251-A1 IONIC HYDROPHILIZED POLYISOCYANATES, WATER CONTENT Covestro Intellectual Property GmbH & Co. KG (DE) 2020-10-21 EP disclosed
CN-110396165-A Ionic hydrophilic polyisocyanates and antioxidant COVESTRO DEUTSCHLAND AG 2019-11-01 CN disclosed
CN-110396173-A Ionic hydrophilic polyisocyanates and free radical scavenger and/or peroxide decomposer COVESTRO DEUTSCHLAND AG 2019-11-01 CN disclosed