Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5202071 | 1.00 | — | — | |
| SCHEMBL196408 | 0.95 | — | — | |
| SCHEMBL372610 | 0.95 | — | — | |
| SCHEMBL135308 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL135306 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL135307 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL842523 | 0.92 | — | — | |
| Bromide SCHEMBL5401276 | 0.92 | — | — | |
| Bromide SCHEMBL5401279 | 0.92 | — | — | |
| Water SCHEMBL28328236 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113552265-B | Method for detecting impurities in raw materials for synthesizing propane fumarate tenofovir and application | 天地恒一制药股份有限公司 | 2022-01-04 | — | — | CN | disclosed |
| CN-113552265-A | Method for detecting impurities in raw materials for synthesizing propane fumarate tenofovir and application | 天地恒一制药股份有限公司 | 2021-10-26 | — | — | CN | disclosed |
| EP-3219335-B1 | COATING COMPOSITION AND MEDICAL DEVICE | TERUMO CORP (JP) | 2018-12-19 | — | — | EP | disclosed |
| EP-3219335-A1 | COATING COMPOSITION AND MEDICAL DEVICE | Terumo Kabushiki Kaisha (JP) | 2017-09-20 | — | — | EP | disclosed |
| WO-2017102802-A1 | RESORCINOL DERIVATIVES FOR THEIR COSMETIC USE | L'OREAL (FR) | 2017-06-22 | — | — | WO | disclosed |
| US-20170143663-A1 | COATING COMPOSITION AND MEDICAL DEVICE | TERUMO KABUSHIKI KAISHA (JP) | 2017-05-25 | — | — | US | disclosed |
| US-9603974-B2 | Coating composition and medical device | TERUMO KABUSHIKI KAISHA (JP) | 2017-03-28 | — | — | US | disclosed |
| US-9592322-B2 | Coating composition and medical device | TERUMO KABUSHIKI KAISHA (JP) | 2017-03-14 | — | — | US | disclosed |
| EP-2801379-B1 | COATING COMPOSITION AND MEDICAL DEVICE | TERUMO CORP (JP) | 2017-03-08 | — | — | EP | disclosed |
| US-20150057746-A1 | COATING COMPOSITION AND MEDICAL DEVICE | TERUMO KABUSHIKI KAISHA (JP) | 2015-02-26 | — | — | US | disclosed |
| US-20150056265-A1 | COATING COMPOSITION AND MEDICAL DEVICE | TERUMO KABUSHIKI KAISHA (JP) | 2015-02-26 | — | — | US | disclosed |
| EP-2234978-B1 | CARBAMOYL COMPOUNDS AS DGAT1 INHIBITORS 190 | ASTRAZENECA AB (SE) | 2015-02-25 | — | — | EP | disclosed |
| EP-2801379-A1 | COATING COMPOSITION AND MEDICAL DEVICE | Terumo Kabushiki Kaisha (JP) | 2014-11-12 | — | — | EP | disclosed |
| CN-101932562-B | Carbamoyl compounds as dgat1 inhibitors 190 | ASTRAZENECA AB | 2013-06-12 | — | — | CN | disclosed |
| US-20120108602-A1 | Carbamoyl Compounds as DGAT1 Inhibitors 190 | ASTRAZENECA AB (SE) | 2012-05-03 | — | — | US | disclosed |
| US-7994179-B2 | Carbamoyl compounds as DGAT1 inhibitors 190 | ASTRAZENECA AB (SE) | 2011-08-09 | — | — | US | disclosed |
| CN-101932562-A | Carbamoyl compounds as dgat1 inhibitors 190 | ASTRAZENECA AB | 2010-12-29 | — | — | CN | disclosed |
| EP-2234978-A1 | CARBAMOYL COMPOUNDS AS DGAT1 INHIBITORS 190 | AstraZeneca AB (SE) | 2010-10-06 | — | — | EP | disclosed |
| US-20090298853-A1 | Carbamoyl Compounds as DGAT1 Inhibitors 190 | ASTRAZENECA AB (SE) | 2009-12-03 | — | — | US | disclosed |
| WO-2009081195-A1 | CARBAMOYL COMPOUNDS AS DGAT1 INHIBITORS 190 | ASTRAZENECA AB (SE) | 2009-07-02 | — | — | WO | disclosed |