Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | GSK3B | P49841 | 2/20 | 0.58 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5990135 | 0.84 | TSHR (0.61) | TSHRALDH1A1MAPK1GSK3BTRPA1 | |
| SCHEMBL5158714 | 0.83 | TSHR (0.59) | TSHRALDH1A1MAPK1GSK3BTRPA1 | |
| SCHEMBL2598225 | 0.83 | TSHR (0.59) | TSHRALDH1A1MAPK1GSK3BTRPA1 | |
| SCHEMBL8898345 | 0.83 | TSHR (0.59) | TSHRALDH1A1MAPK1GSK3BTRPA1 | |
| SCHEMBL28481770 | 0.83 | TSHR (0.59) | TSHRALDH1A1MAPK1GSK3BTRPA1 | |
| SCHEMBL5552472 | 0.83 | TSHR (0.64) | TSHRALDH1A1MAPK1GSK3BTRPA1 | |
| SCHEMBL9720592 | 0.81 | ALDH1A1 (0.57) | TSHRALDH1A1MAPK1GSK3BTRPA1 | |
| SCHEMBL8534214 | 0.81 | TSHR (0.57) | TSHRALDH1A1MAPK1GSK3BTRPA1 | |
| SCHEMBL6425252 | 0.80 | TSHR (0.61) | TSHRALDH1A1MAPK1GSK3BTRPA1 | |
| SCHEMBL7436608 | 0.79 | TSHR (0.55) | TSHRALDH1A1MAPK1GSK3BTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115436507-A | Method for detecting content of 3,4' -dichloropropiophenone | 山东京博生物科技有限公司 | 2022-12-06 | — | — | CN | claimed |
| CN-111454137-B | Synthetic method for improving yield of 5-chloro-1-indanone | 山东京博生物科技有限公司 | 2022-09-23 | — | — | CN | claimed |
| CN-111454137-A | Synthetic method for improving yield of 5-chloro-1-indanone | 山东京博生物科技有限公司 | 2020-07-28 | — | — | CN | claimed |
| CN-111205175-A | Synthetic method for improving yield of 5-chloro-1-indanone | 京博农化科技有限公司 | 2020-05-29 | — | — | CN | claimed |
| CN-107118103-A | A kind of insecticide indoxacarb intermediate and its synthesis technique | 连云港市国盛化工有限公司 | 2017-09-01 | — | — | CN | claimed |
| CN-1403434-A | Prepn process of 5-chloro-2,3-dihydro-1-indenone | WANG MINGCHUN (CN) | 2003-03-19 | — | — | CN | claimed |
| CN-115436507-A | Method for detecting content of 3,4' -dichloropropiophenone | 山东京博生物科技有限公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-111454137-B | Synthetic method for improving yield of 5-chloro-1-indanone | 山东京博生物科技有限公司 | 2022-09-23 | — | — | CN | disclosed |
| CN-111454137-A | Synthetic method for improving yield of 5-chloro-1-indanone | 山东京博生物科技有限公司 | 2020-07-28 | — | — | CN | disclosed |
| CN-111205175-A | Synthetic method for improving yield of 5-chloro-1-indanone | 京博农化科技有限公司 | 2020-05-29 | — | — | CN | disclosed |
| CN-104910001-B | A kind of synthetic method of the chloro- 1- indones of new 5- | 上海博栋化学科技有限公司 | 2018-10-16 | — | — | CN | disclosed |
| CN-107118103-A | A kind of insecticide indoxacarb intermediate and its synthesis technique | 连云港市国盛化工有限公司 | 2017-09-01 | — | — | CN | disclosed |
| CN-105263902-B | The improved method for preparing specific oxime and oxime ether | 拜耳作物科学股份公司 | 2017-07-25 | — | — | CN | disclosed |
| EP-1605078-A1 | NOVEL IMIDAZOLE COMPOUND AND USAGE THEREOF | SHIKOKU CHEMICALS CORPORATION (JP) | 2005-12-14 | — | — | EP | disclosed |
| CN-1403434-A | Prepn process of 5-chloro-2,3-dihydro-1-indenone | WANG MINGCHUN (CN) | 2003-03-19 | — | — | CN | disclosed |
| WO-2000075094-A2 | METHOD FOR PRODUCING A HALOGENATED ACETOPHENONE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2000-12-14 | — | — | WO | disclosed |
| CN-1028229-C | Heterocyclic compounds containing nitrogen and sulfur, pharmaceutical composition containing same and process for preparing them | RICHTER GEDEON VEGYESZET (HU) | 1995-04-19 | — | — | CN | disclosed |
| US-5096902-A | Cerebral antihypoxic action, senile dememtia, Alzheimer's, cognitive functions | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1992-03-17 | — | — | US | disclosed |
| CN-1049159-A | The heterogeneous ring compound of new nitrogenous and sulphur, the method that contains the pharmaceutical composition of this compounds and prepare them | RICHTER GEDEON VEGYESZET (HU) | 1991-02-13 | — | — | CN | disclosed |
| EP-0144729-A1 | 11-Substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines, a process for their preparation and their use in medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1985-06-19 | — | — | EP | disclosed |