Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 7/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | YAP1 | P46937 | 1/20 | 0.43 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.43 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22556586 | 0.78 | CDC25B (0.56) | TAS2R14MAPTHTTNPSR1 | |
| SCHEMBL20553269 | 0.77 | RXFP1 (0.58) | TAS2R14RXFP1AKR1C3AKR1C2MAPK8 | |
| SCHEMBL25279533 | 0.76 | AKR1C3 (0.60) | TAS2R14RXFP1AKR1C3AKR1C2MAPK8 | |
| SCHEMBL22571369 | 0.76 | SIRT2 (0.62) | TAS2R14RXFP1MAPK8PTGS1SIRT2 | |
| SCHEMBL22571350 | 0.76 | RXFP1 (0.51) | TAS2R14RXFP1AKR1C3AKR1C2MAPK8 | |
| SCHEMBL4245559 | 0.75 | MAPK8 (0.67) | TAS2R14RXFP1AKR1C3AKR1C2MAPK8 | |
| SCHEMBL21765032 | 0.74 | MAPT (0.69) | TAS2R14RXFP1AKR1C3AKR1C2MAPK8 | |
| SCHEMBL21764748 | 0.74 | RXFP1 (0.47) | TAS2R14RXFP1AKR1C3AKR1C2MAPK8 | |
| SCHEMBL23388931 | 0.73 | MAPK8 (0.38) | TAS2R14RXFP1AKR1C3AKR1C2MAPK8 | |
| SCHEMBL28322767 | 0.71 | TSHR (0.56) | TAS2R14SIRT2MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793551-A1 | OXADIAZOLE COMPOUNDS | Vivace Therapeutics, Inc. (US) | 2021-03-24 | — | — | EP | disclosed |
| WO-2019222431-A9 | OXADIAZOLE COMPOUNDS | VIVACE THERAPEUTICS, INC. (US) | 2020-10-22 | — | — | WO | disclosed |