Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 6/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29888201 | 0.83 | RXFP1 (0.42) | MAPK8RXFP1TAS2R14AKR1C3AKR1C2 | |
| SCHEMBL23388810 | 0.83 | RXFP1 (0.42) | MAPK8RXFP1TAS2R14AKR1C3AKR1C2 | |
| SCHEMBL22571385 | 0.77 | RXFP1 (0.43) | MAPK8RXFP1TAS2R14AKR1C3AKR1C2 | |
| SCHEMBL23388914 | 0.76 | JAK2 (0.39) | AURKAAURKBMAPTJAK2JAK1 | |
| SCHEMBL22556550 | 0.73 | TAS2R14 (0.44) | MAPK8RXFP1TAS2R14AKR1C3AKR1C2 | |
| SCHEMBL23423242 | 0.73 | LMNA (0.45) | PTGS1MEN1MAPTRAB9AKMT2A | |
| SCHEMBL29888273 | 0.73 | POLB (0.41) | PTGS1MEN1MAPTHTTRAB9A | |
| SCHEMBL23389117 | 0.73 | POLB (0.41) | PTGS1MEN1MAPTHTTRAB9A | |
| SCHEMBL23388930 | 0.69 | EPHX2 (0.41) | MAPK8RXFP1TAS2R14AKR1C3AKR1C2 | |
| SCHEMBL30323356 | 0.69 | TLR7 (0.43) | RXFP1AURKAAURKBJAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021102204-A1 | HETEROARYL COMPOUNDS | VIVACE THERAPEUTICS, INC. (US) | 2021-05-27 | — | — | WO | disclosed |