Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | FLT4 | P35916 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29394070 | 1.00 | VCP (0.52) | VCPFAAHHDAC1HDAC6DYRK1A | |
| SCHEMBL22556757 | 0.87 | BRD4 (0.46) | VCPKDM4EMAPTTDP1ALDH1A1 | |
| SCHEMBL22570681 | 0.82 | PRMT1 (0.44) | DYRK1ACYP3A4 | |
| SCHEMBL5639075 | 0.82 | HDAC1 (0.53) | FAAHHDAC1HDAC6KDM4EMAPT | |
| SCHEMBL5472146 | 0.81 | VCP (0.55) | VCPFAAHHDAC1HDAC6DYRK1A | |
| SCHEMBL22556766 | 0.80 | NOTUM (0.40) | VCPHDAC1HDAC6FLT1FLT4 | |
| SCHEMBL29393846 | 0.79 | FFAR1 (0.52) | VCPHDAC1HDAC6FLT1FLT4 | |
| SCHEMBL20600253 | 0.79 | FFAR1 (0.52) | VCPHDAC1HDAC6FLT1FLT4 | |
| SCHEMBL22556758 | 0.79 | NOTUM (0.54) | HDAC1HDAC6FLT1FLT4KDR | |
| SCHEMBL2406093 | 0.79 | VCP (0.56) | VCPFAAHDYRK1ACLK4FLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3956323-A1 | OXAZOLE AND OXADIAZOLE DERIVATIVES USEFUL AS AGONISTS OF FREE FATTY ACID RECEPTOR 1 | Gbiotech S.À.R.L. (CH) | 2022-02-23 | — | — | EP | disclosed |
| WO-2020211956-A1 | OXAZOLE AND OXADIAZOLE DERIVATIVES USEFUL AS AGONISTS OF FREE FATTY ACID RECEPTOR 1 | GBIOTECH S.À.R.L. (CH) | 2020-10-22 | — | — | WO | disclosed |