Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 10/20 | 0.69 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.69 |
| ▸ | PI4KA | P42356 | 3/20 | 0.69 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.69 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.69 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.69 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | AHCY | P23526 | 7/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16762626 | 0.86 | ADORA2A (0.71) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL11222112 | 0.85 | ADORA2A (0.80) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL12925855 | 0.83 | ADORA2A (0.71) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL6029105 | 0.82 | ADORA2A (0.71) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL1871838 | 0.81 | ADORA2A (0.75) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL1924594 | 0.81 | ADORA2A (1.00) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL2495370 | 0.81 | ADORA2A (0.69) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL2561529 | 0.81 | AHCY (0.66) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL7680204 | 0.81 | AHCY (0.66) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL2638103 | 0.80 | ADORA2A (0.73) | ADORA2AADORA1PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020212995-A1 | HIGHLY SELECTIVE AND POTENT NPP1 INHIBITORS BASED ON URIDINE-5'-P,-DITHIOPHOSPHATE ANALOGUES | BAR-ILAN UNIVERSITY (IL) | 2020-10-22 | — | — | WO | disclosed |