Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | TACR2 | P21452 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21338622 | 0.77 | DDB1 (0.46) | DDB1CRBNHDAC8HSD11B1MAOB | |
| SCHEMBL2793462 | 0.77 | DDB1 (0.46) | DDB1CRBNHDAC8HSD11B1MAOB | |
| SCHEMBL17136803 | 0.77 | DDB1 (0.46) | DDB1CRBNHDAC8HSD11B1MAOB | |
| SCHEMBL7451040 | 0.77 | DDB1 (0.46) | DDB1CRBNHDAC8 | |
| SCHEMBL4293099 | 0.77 | DDB1 (0.46) | DDB1CRBNHDAC8 | |
| SCHEMBL6412785 | 0.77 | DDB1 (0.46) | DDB1CRBNHDAC8HSD11B1MAOB | |
| SCHEMBL4293100 | 0.77 | DDB1 (0.46) | DDB1CRBNHDAC8 | |
| SCHEMBL9312858 | 0.76 | DDB1 (0.45) | DDB1CRBN | |
| SCHEMBL22728222 | 0.74 | DDB1 (0.44) | DDB1CRBNHDAC8HSD11B1MAOB | |
| SCHEMBL22649563 | 0.74 | HDAC1 (0.43) | HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10808059-B2 | Polymer | CANON KABUSHIKI KAISHA (JP) | 2020-10-20 | — | — | US | disclosed |