Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 10/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 5/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7451040 | 1.00 | DDB1 (0.46) | DDB1CRBNMMECTSDBACE1 | |
| SCHEMBL4293099 | 1.00 | DDB1 (0.46) | DDB1CRBNMMECTSDBACE1 | |
| SCHEMBL2578395 | 0.84 | CTSD (0.45) | DDB1CRBNCTSDBACE1MMP13 | |
| SCHEMBL4302079 | 0.84 | CTSD (0.45) | DDB1CRBNCTSDBACE1MMP13 | |
| SCHEMBL7057956 | 0.82 | KDM4E (0.45) | MMEACEHDAC8 | |
| SCHEMBL2790837 | 0.82 | MEN1 (0.45) | DDB1CRBNCTSDBACE1 | |
| SCHEMBL2790835 | 0.82 | MEN1 (0.45) | DDB1CRBNCTSDBACE1 | |
| SCHEMBL22980561 | 0.81 | BCHE (0.44) | MMEACEMMP13 | |
| SCHEMBL29200800 | 0.81 | BCHE (0.44) | MMEACEMMP13 | |
| SCHEMBL29200798 | 0.81 | BCHE (0.44) | MMEACEMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009038412-A2 | BETA-SECRETASE INHIBITING COMPOUNDS | LG LIFE SCIENCES, LTD. (KR) | 2009-03-26 | — | — | WO | disclosed |