Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1318677 | 0.82 | MEN1 (0.39) | TSHRMEN1NPC1RAB9AKMT2A | |
| SCHEMBL24844526 | 0.79 | TSHR (0.38) | TSHRMEN1NPC1RAB9AKMT2A | |
| SCHEMBL13230696 | 0.78 | TSHR (0.44) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL13201253 | 0.74 | TSHR (0.36) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL22560135 | 0.74 | TSHR (0.41) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL1723604 | 0.73 | TSHR (0.57) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL347559 | 0.73 | TSHR (0.57) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL20089024 | 0.72 | TSHR (0.35) | TSHRMEN1NPC1RAB9AKMT2A | |
| SCHEMBL9242015 | 0.72 | TSHR (0.42) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL19245944 | 0.72 | TSHR (0.42) | TSHRMEN1KMT2AALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3638705-B1 | INTRAOCULAR LENS COMPOSITIONS | ALCON INC (CH) | 2024-02-28 | — | — | EP | disclosed |
| US-11642217-B2 | Intraocular lens compositions | ALCON INC. (CH) | 2023-05-09 | — | — | US | disclosed |
| US-11642217-B2 | Intraocular lens compositions | ALCON INC. (CH) | 2023-05-09 | — | — | US | disclosed |
| US-20200405474-A1 | INTRAOCULAR LENS COMPOSITIONS | ALCON RESEARCH, LTD. | 2020-12-31 | — | — | US | disclosed |
| US-10806566-B2 | Intraocular lens compositions | ALCON INC. (CH) | 2020-10-20 | — | — | US | disclosed |