Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | HTT | P42858 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 6/20 | 0.51 |
| ▸ | THRB | P10828 | 5/20 | 0.51 |
| ▸ | RECQL | P46063 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | BLM | P54132 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL22542632 | 0.99 | MEN1 (0.50) | MEN1KMT2AMAPTHTTLMNA | |
| Iodide SCHEMBL22542633 | 0.99 | MEN1 (0.50) | MEN1KMT2AMAPTHTTLMNA | |
| SCHEMBL22560153 | 0.93 | MEN1 (0.50) | MEN1KMT2AMAPTHTTLMNA | |
| Iodide SCHEMBL22542611 | 0.92 | MEN1 (0.49) | MEN1KMT2AMAPTHTTLMNA | |
| Iodide SCHEMBL22542630 | 0.88 | MAPT (0.49) | MEN1KMT2AMAPTHTTLMNA | |
| Iodide SCHEMBL22542631 | 0.88 | MAPT (0.49) | MEN1KMT2AMAPTHTTLMNA | |
| SCHEMBL13235658 | 0.87 | ACHE (0.52) | MEN1KMT2AMAPTHTTLMNA | |
| Iodide SCHEMBL22542615 | 0.85 | PRMT1 (0.53) | MEN1KMT2AMAPTHTTLMNA | |
| Iodide SCHEMBL22542614 | 0.85 | PRMT1 (0.53) | MEN1KMT2AMAPTHTTLMNA | |
| SCHEMBL25416827 | 0.84 | MAPT (0.57) | MEN1KMT2AMAPTHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10808128-B2 | Compounds as fluorescent probes, synthesis and applications thereof | INSTITUTE FOR STEM CELL BIOLOGY AND REGENERATIVE MEDICINE (INSTEM) (IN) | 2020-10-20 | — | — | US | disclosed |