Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22561935 | 0.84 | — | — | |
| SCHEMBL22562067 | 0.81 | CYP2D6 (0.40) | CYP2D6 | |
| SCHEMBL22562006 | 0.78 | — | — | |
| SCHEMBL18432558 | 0.71 | MEN1 (0.36) | MEN1KMT2ACYP2D6 | |
| SCHEMBL22561910 | 0.71 | — | — | |
| SCHEMBL22561897 | 0.69 | — | — | |
| SCHEMBL20009402 | 0.67 | MEN1 (0.32) | MEN1KMT2ACYP2D6 | |
| SCHEMBL25886732 | 0.65 | MEN1 (0.40) | GABRA1GABRG2GABRB3GABRB2MEN1 | |
| SCHEMBL21022125 | 0.64 | GABRA1 (0.36) | GABRA1GABRG2GABRB3GABRB2 | |
| SCHEMBL19370572 | 0.64 | TDP1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191467-B1 | COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2020-10-21 | — | — | EP | disclosed |