Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 6/20 | 0.44 |
| ▸ | SAT1 | P21673 | 3/20 | 0.43 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA3 | P07451 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10045114 | 0.98 | CYP2C19 (0.59) | CYP2C19MEN1KMT2AGLACYP1A2 | |
| SCHEMBL10045090 | 0.87 | PAOX (0.43) | CYP2C19MEN1KMT2AGLACYP1A2 | |
| SCHEMBL20782952 | 0.87 | CYP2C19 (0.46) | CYP2C19MEN1KMT2AGLACYP1A2 | |
| SCHEMBL112008 | 0.79 | CYP2C19 (0.46) | CYP2C19MEN1KMT2AGLACYP1A2 | |
| SCHEMBL10045071 | 0.77 | CA12 (0.50) | CYP2C19MEN1KMT2ACYP1A2TSHR | |
| SCHEMBL12091637 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL31441106 | 0.77 | CYP2C19 (0.44) | CYP2C19MEN1KMT2AGLACYP1A2 | |
| SCHEMBL24103200 | 0.76 | KDM4E (0.52) | MEN1KMT2APAOXKDM4EMAPK1 | |
| SCHEMBL17035521 | 0.76 | PAOX (0.65) | CYP2C19MEN1KMT2AGLACYP1A2 | |
| SCHEMBL15787326 | 0.76 | CYP2C19 (0.55) | CYP2C19MEN1KMT2AGLACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3725780-A1 | SULFONAMIDE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE ACID-ADDITION SALT | University of Tsukuba (JP) | 2020-10-21 | — | — | EP | disclosed |