SCHEMBL22563675

SCHEMBL22563675

Cc1cc(C)nc(-c2cc(-n3c4cc(-c5cc(C#N)cc(C#N)c5)ccc4c4ccc(-c5cc(C#N)cc(C#N)c5)cc43)c(C#N)c(-n3c4cc(-c5cc(C#N)cc(C#N)c5)ccc4c4ccc(-c5cc(C#N)cc(C#N)c5)cc43)c2)n1

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 3/20 0.34
IRAK4 Q9NWZ3 1/20 0.34
CHEK1 O14757 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22563377 0.95 ABCG2 (0.36) ABCG2IRAK4
SCHEMBL22563378 0.92 CHEK1 (0.40) ABCG2IRAK4CHEK1
SCHEMBL19909209 0.92 METAP2 (0.36) IRAK4CHEK1
SCHEMBL23487784 0.91 ABCG2 (0.45) ABCG2IRAK4
SCHEMBL19943076 0.91 CHEK1 (0.33) CHEK1
SCHEMBL23487302 0.89 KDM5B (0.40) ABCG2IRAK4
SCHEMBL23487305 0.88 NPSR1 (0.37) ABCG2CHEK1
SCHEMBL23487667 0.88 ABCG2 (0.39) ABCG2
SCHEMBL23487785 0.87 ABCG2 (0.44) ABCG2
SCHEMBL22563573 0.87 KDM4E (0.40) ABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3580300-B1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-10-21 EP disclosed