SCHEMBL22563748

SCHEMBL22563748

Cc1ccc(S(=O)(=O)N2c3ccccc3NC(=O)C2CC(=O)NCc2ccc(NCCF)cc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.66
POLB P06746 1/20 0.66
BDKRB1 P46663 17/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15599337 1.00 ALDH1A1 (0.66) ALDH1A1POLBBDKRB1
SCHEMBL15599428 0.93 ALDH1A1 (0.65) ALDH1A1POLBBDKRB1
SCHEMBL4424964 0.89 ALDH1A1 (0.76) ALDH1A1POLBBDKRB1
SCHEMBL22563749 0.86 ALDH1A1 (0.77) ALDH1A1POLBBDKRB1
SCHEMBL20457664 0.81 ALDH1A1 (0.77) ALDH1A1POLBBDKRB1
SCHEMBL6029674 0.80 ALDH1A1 (1.00) ALDH1A1POLBBDKRB1
SCHEMBL6403536 0.80 ALDH1A1 (1.00) ALDH1A1POLBBDKRB1
SCHEMBL15599334 0.77 ALDH1A1 (0.77) ALDH1A1POLBBDKRB1
SCHEMBL4425350 0.77 ALDH1A1 (0.58) ALDH1A1POLBBDKRB1
SCHEMBL6406112 0.77 BDKRB1 (0.67) ALDH1A1POLBBDKRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2895204-B1 COMPOSITIONS TARGETING BRADYKININ RECEPTOR B1 FOR MEDICAL IMAGING OF CANCER AND OTHER DISORDERS PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2020-10-21 EP disclosed