Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22564181 | 0.90 | NR1H4 (0.41) | NR1H4GABRA1GABRG2GABRB3 | |
| SCHEMBL22564126 | 0.89 | NR1H4 (0.36) | NR1H4GABRA1GABRG2GABRB3 | |
| SCHEMBL22563854 | 0.89 | KLKB1 (0.32) | NR1H4 | |
| SCHEMBL22564139 | 0.89 | NR1H4 (0.35) | NR1H4GABRA1GABRG2GABRB3 | |
| SCHEMBL22564094 | 0.89 | NR1H4 (0.37) | NR1H4GABRA1GABRG2GABRB3 | |
| SCHEMBL22564477 | 0.88 | KDM4E (0.38) | NR1H4GABRA1GABRG2GABRB3 | |
| SCHEMBL18504998 | 0.87 | NR1H4 (0.37) | NR1H4GABRA1GABRG2GABRB3 | |
| SCHEMBL22564030 | 0.87 | NPC1 (0.35) | NR1H4GABRA1GABRG2GABRB3 | |
| SCHEMBL22564200 | 0.87 | NR1H4 (0.34) | NR1H4GABRA1GABRG2GABRB3 | |
| SCHEMBL22563916 | 0.86 | TSHR (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |