Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22564230 | 0.92 | ALDH1A1 (0.41) | TSHRJMJD6ALDH1A1HSD17B10MAPK1 | |
| SCHEMBL22563857 | 0.91 | TSHR (0.38) | TSHRJMJD6GABRA5ALDH1A1HSD17B10 | |
| SCHEMBL22564477 | 0.89 | KDM4E (0.38) | KDM4EALDH1A1TDP1TP53 | |
| SCHEMBL18504647 | 0.88 | TSHR (0.40) | TSHRGABRA5KDM4EALDH1A1HSD17B10 | |
| SCHEMBL22564030 | 0.88 | NPC1 (0.35) | TSHRJMJD6GABRA5KDM4EALDH1A1 | |
| SCHEMBL22564213 | 0.87 | TSHR (0.40) | TSHRJMJD6GABRA5KDM4EALDH1A1 | |
| SCHEMBL22564181 | 0.87 | NR1H4 (0.41) | CYP1A2 | |
| SCHEMBL22564101 | 0.87 | TSHR (0.42) | TSHRJMJD6GABRA5KDM4EALDH1A1 | |
| SCHEMBL22564139 | 0.86 | NR1H4 (0.35) | KDM4ESMN1; SMN2TBXAS1 | |
| SCHEMBL22563877 | 0.86 | NR1H4 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |