Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22563974 | 0.90 | SGMS2 (0.38) | SGMS2NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL22564179 | 0.90 | HDAC3 (0.40) | SGMS2NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL22563941 | 0.88 | NR1H4 (0.31) | SGMS2NR1H4PTGDR2 | |
| SCHEMBL18504789 | 0.87 | SGMS2 (0.38) | SGMS2NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL22564531 | 0.87 | SGMS2 (0.38) | SGMS2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL22564062 | 0.87 | SGMS2 (0.35) | SGMS2NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL22564144 | 0.87 | NPC1 (0.36) | NPC1RAB9AHTTSMN1; SMN2LMNA | |
| SCHEMBL22564097 | 0.87 | NR1H4 (0.31) | NR1H4 | |
| SCHEMBL22564137 | 0.86 | SGMS2 (0.37) | SGMS2NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL22564163 | 0.86 | KMT2A (0.32) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |