SCHEMBL22563956

SCHEMBL22563956

CCSc1cccc(C(N)=O)c1COc1ccn(S)n1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 5/20 0.33
MAPK1 P28482 3/20 0.33
LMNA P02545 2/20 0.33
MITF O75030 1/20 0.33
TSHR P16473 1/20 0.33
HTT P42858 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HPGD P15428 5/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
PARP1 P09874 2/20 0.31
ALDH1A1 P00352 4/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ALOX15 P16050 1/20 0.31
MEN1 O00255 1/20 0.30
NR1I2 O75469 1/20 0.30
CHRM2 P08172 1/20 0.30
CYP3A4 P08684 1/20 0.30
ADRA2A P08913 1/20 0.30
MAPT P10636 1/20 0.30
OPRK1 P41145 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22564272 0.90 NR1H4 (0.35) HSD17B10MAPK1LMNAMITFTSHR
SCHEMBL22564337 0.89 HSD17B10 (0.33) HSD17B10MAPK1LMNAMITFTSHR
SCHEMBL22564517 0.89 HSD17B10 (0.33) HSD17B10MAPK1LMNAMITFTSHR
SCHEMBL22564538 0.89
SCHEMBL22564391 0.89 TSHR (0.31) LMNATSHRHTTNPSR1HPGD
SCHEMBL22564478 0.88 HSD17B10 (0.38) HSD17B10MAPK1LMNAMITFTSHR
SCHEMBL18504515 0.88 HSD17B10 (0.36) HSD17B10MAPK1LMNAMITFTSHR
SCHEMBL22564192 0.87 HPGD (0.35) HSD17B10MAPK1LMNAMITFTSHR
SCHEMBL22563939 0.87 TSHR (0.38) HSD17B10MAPK1LMNATSHRNPSR1
SCHEMBL22563986 0.87 HPGD (0.35) HSD17B10MAPK1LMNAMITFTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2841429-B1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2020-10-21 EP disclosed