Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | NMT2 | O60551 | 1/20 | 0.35 |
| ▸ | NMT1 | P30419 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22564494 | 0.92 | ALDH1A1 (0.40) | TSHRALDH1A1LMNANPSR1JMJD6 | |
| SCHEMBL22564208 | 0.92 | TSHR (0.36) | TSHRALDH1A1LMNANPSR1JMJD6 | |
| SCHEMBL22564491 | 0.91 | ALDH1A1 (0.45) | TSHRALDH1A1LMNANPSR1JMJD6 | |
| SCHEMBL22564478 | 0.91 | HSD17B10 (0.38) | TSHRALDH1A1LMNANPSR1HSD17B10 | |
| SCHEMBL18504389 | 0.88 | TSHR (0.39) | TSHRALDH1A1LMNANPSR1GABRA5 | |
| SCHEMBL22564272 | 0.88 | NR1H4 (0.35) | TSHRALDH1A1LMNANPSR1HSD17B10 | |
| SCHEMBL22564282 | 0.88 | ALDH1A1 (0.34) | TSHRALDH1A1LMNANPSR1JMJD6 | |
| SCHEMBL22563956 | 0.87 | HSD17B10 (0.33) | TSHRALDH1A1LMNANPSR1HSD17B10 | |
| SCHEMBL22564517 | 0.87 | HSD17B10 (0.33) | TSHRALDH1A1LMNANPSR1HSD17B10 | |
| SCHEMBL22564337 | 0.87 | HSD17B10 (0.33) | TSHRALDH1A1LMNANPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |