Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22564477 | 0.90 | KDM4E (0.38) | KDM4EKMT2AGAAATMALDH1A1 | |
| SCHEMBL22563880 | 0.89 | MAPT (0.36) | KDM4EKMT2AKLKB1ALDH1A1LMNA | |
| SCHEMBL22563857 | 0.89 | TSHR (0.38) | KMT2AATMALDH1A1HSD17B10POLB | |
| SCHEMBL18504522 | 0.88 | KDM4E (0.36) | KDM4EKMT2AGAAATMKLKB1 | |
| SCHEMBL22563852 | 0.88 | NR1H4 (0.35) | KLKB1 | |
| SCHEMBL22564499 | 0.88 | ALDH1A1 (0.40) | KDM4EKMT2AATMALDH1A1HSD17B10 | |
| SCHEMBL22564363 | 0.87 | KLKB1 (0.35) | KLKB1 | |
| SCHEMBL22564210 | 0.87 | KLKB1 (0.33) | KLKB1 | |
| SCHEMBL22563854 | 0.87 | KLKB1 (0.32) | KLKB1 | |
| SCHEMBL22564140 | 0.87 | PARP1 (0.32) | KMT2AKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |