SCHEMBL22564052

SCHEMBL22564052

CCCOC(=O)c1cccc(OC(F)(F)F)c1COc1ccn(S)n1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
PDK2 Q15119 1/20 0.37
JMJD6 Q6NYC1 1/20 0.34
F2R P25116 1/20 0.34
SCN9A Q15858 1/20 0.34
TSHR P16473 3/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HCRTR1 O43613 6/20 0.33
HCRTR2 O43614 6/20 0.33
TBXAS1 P24557 1/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
MAPK1 P28482 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22564302 0.92 SCN9A (0.40) ALDH1A1PDK2JMJD6SCN9ATSHR
SCHEMBL18504662 0.89 ALDH1A1 (0.40) ALDH1A1PDK2JMJD6F2RSCN9A
SCHEMBL22564187 0.88 ALDH1A1 (0.40) ALDH1A1PDK2JMJD6TSHRTDP1
SCHEMBL22563985 0.88 ALDH1A1 (0.42) ALDH1A1JMJD6TSHRTDP1L3MBTL1
SCHEMBL22564284 0.88 ALDH1A1 (0.42) ALDH1A1PDK2JMJD6TSHRTDP1
SCHEMBL22564482 0.88 KCNK3 (0.36) ALDH1A1F2RHCRTR1HCRTR2MAPT
SCHEMBL22564039 0.86 ALDH1A1 (0.39) ALDH1A1PDK2JMJD6TSHRTDP1
SCHEMBL22564229 0.86 ALDH1A1 (0.40) ALDH1A1PDK2JMJD6TSHRTDP1
SCHEMBL22563881 0.85 KCNK3 (0.36) PDK2JMJD6F2RSCN9AL3MBTL1
SCHEMBL22563860 0.85 ALDH1A1 (0.40) ALDH1A1JMJD6TSHRTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2841429-B1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2020-10-21 EP disclosed