Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.33 |
| ▸ | MT-CO1 | P00395 | 1/20 | 0.33 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.33 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22978084 | 0.86 | — | — | |
| SCHEMBL2520234 | 0.80 | — | — | |
| SCHEMBL18071031 | 0.80 | — | — | |
| SCHEMBL2520237 | 0.80 | — | — | |
| SCHEMBL2521937 | 0.80 | — | — | |
| SCHEMBL20124555 | 0.80 | SHBG (0.31) | MAN1B1 | |
| SCHEMBL16705451 | 0.79 | CA1 (0.39) | CA1CA2CA4PTGS1PTGS2 | |
| SCHEMBL12166760 | 0.79 | CA1 (0.46) | CA1CA2CA4PTGS1PTGS2 | |
| Hydrochloric Acid SCHEMBL14861581 | 0.78 | — | — | |
| SCHEMBL12167126 | 0.76 | JAK2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3725310-A1 | USE OF PHARMACOLOGICAL CHAPERONES FOR THE TREATMENT OF LYSOSOMAL STORAGE DISEASES | Fundación Biomédica Galicia Sur (ES) | 2020-10-21 | — | — | EP | disclosed |