Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 19/20 | 0.48 |
| ▸ | ESRRA | P11474 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28675414 | 0.85 | AR (0.46) | AR | |
| SCHEMBL24266783 | 0.83 | AR (0.64) | AR | |
| SCHEMBL19600753 | 0.82 | AR (0.64) | AR | |
| SCHEMBL24266949 | 0.82 | AR (0.64) | AR | |
| SCHEMBL24266716 | 0.78 | AR (0.67) | AR | |
| SCHEMBL22564874 | 0.78 | AR (0.67) | AR | |
| SCHEMBL22565333 | 0.76 | AR (0.32) | AR | |
| SCHEMBL22565992 | 0.75 | AR (0.58) | AR | |
| SCHEMBL22557713 | 0.75 | AR (0.58) | AR | |
| SCHEMBL22565508 | 0.75 | PGR (0.46) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3957633-A1 | A CLASS OF BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUNDS FOR TARGETED DEGRADATION OF ANDROGEN RECEPTORS AND USE THEREOF | Hinova Pharmaceuticals Inc. (CN) | 2022-02-23 | — | — | EP | disclosed |
| WO-2020211822-A1 | A CLASS OF BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUNDS FOR TARGETED DEGRADATION OF ANDROGEN RECEPTORS AND USE THEREOF | 成都海创药业有限公司 | 2020-10-22 | — | — | WO | disclosed |