Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 18/20 | 0.75 |
| ▸ | DDB1 | Q16531 | 10/20 | 0.54 |
| ▸ | IKZF3 | Q9UKT9 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TNF | P01375 | 2/20 | 0.45 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.45 |
| ▸ | IL1B | P01584 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22565044 | 0.97 | CRBN (0.74) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL26480838 | 0.91 | CRBN (0.65) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL26111363 | 0.88 | CRBN (0.79) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL30606686 | 0.87 | CRBN (0.66) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL31586405 | 0.86 | CRBN (0.67) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL23152112 | 0.86 | CRBN (0.77) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL22565244 | 0.86 | CRBN (1.00) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL29330488 | 0.86 | CRBN (0.80) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL22557468 | 0.85 | CRBN (0.79) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL31583413 | 0.85 | CRBN (0.66) | CRBNDDB1IKZF3ALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020211822-A1 | A CLASS OF BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUNDS FOR TARGETED DEGRADATION OF ANDROGEN RECEPTORS AND USE THEREOF | 成都海创药业有限公司 | 2020-10-22 | — | — | WO | disclosed |