SCHEMBL31583413

SCHEMBL31583413

O=C1CCC(N2C(=O)c3cc(F)c(N4CCC(N5CC6(CNC6)C5)CC4)cc3C2=O)C(=O)N1

nearest known ligand 0.66

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 17/20 0.66
▸ DDB1 Q16531 9/20 0.49
▸ ALDH1A1 P00352 1/20 0.45
▸ CHRM2 P08172 1/20 0.45
▸ OPRM1 P35372 1/20 0.45
▸ IKZF3 Q9UKT9 1/20 0.45
▸ CYP1A2 P05177 1/20 0.45
▸ TSHR P16473 1/20 0.45
▸ TDP1 Q9NUW8 1/20 0.45
▸ IKZF1 Q13422 2/20 0.42
▸ IKZF2 Q9UKS7 2/20 0.42
▸ TNF P01375 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30703625 0.89 CRBN (0.68) CRBNDDB1ALDH1A1CHRM2OPRM1
SCHEMBL22565343 0.87 CRBN (0.72) CRBNDDB1ALDH1A1CHRM2OPRM1
SCHEMBL30938292 0.86 CRBN (0.62) CRBNDDB1ALDH1A1CHRM2OPRM1
SCHEMBL22565404 0.85 CRBN (0.66) CRBNDDB1ALDH1A1CHRM2OPRM1
SCHEMBL22566049 0.85 CRBN (0.75) CRBNDDB1ALDH1A1CHRM2OPRM1
SCHEMBL22565044 0.84 CRBN (0.74) CRBNDDB1ALDH1A1CHRM2OPRM1
SCHEMBL26110157 0.84 CRBN (0.76) CRBNDDB1ALDH1A1CHRM2OPRM1
SCHEMBL30569096 0.84 CRBN (0.76) CRBNDDB1ALDH1A1CHRM2OPRM1
SCHEMBL26111363 0.83 CRBN (0.79) CRBNDDB1ALDH1A1CHRM2OPRM1
SCHEMBL31306584 0.83 CRBN (0.66) CRBNDDB1ALDH1A1CHRM2OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025106910-A1 DEGRADER MOLECULES TARGETING ANDROGEN RECEPTOR FLARE THERAPEUTICS INC. (US) 2025-05-22 — — WO disclosed
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