Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 18/20 | 0.73 |
| ▸ | KIT | P10721 | 7/20 | 0.73 |
| ▸ | FLT3 | P36888 | 7/20 | 0.73 |
| ▸ | KDR | P35968 | 6/20 | 0.73 |
| ▸ | EGFR | P00533 | 5/20 | 0.73 |
| ▸ | AXL | P30530 | 5/20 | 0.73 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.73 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.73 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.73 |
| ▸ | MST1R | Q04912 | 3/20 | 0.73 |
| ▸ | FLT4 | P35916 | 2/20 | 0.73 |
| ▸ | FLT1 | P17948 | 2/20 | 0.73 |
| ▸ | PLK4 | O00444 | 2/20 | 0.73 |
| ▸ | AURKA | O14965 | 2/20 | 0.73 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.73 |
| ▸ | STK10 | O94804 | 2/20 | 0.73 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.73 |
| ▸ | FYN | P06241 | 2/20 | 0.73 |
| ▸ | YES1 | P07947 | 2/20 | 0.73 |
| ▸ | LYN | P07948 | 2/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29693458 | 1.00 | MET (0.73) | METKITFLT3KDREGFR | |
| SCHEMBL372270 | 1.00 | MET (0.73) | METKITFLT3KDREGFR | |
| SCHEMBL371938 | 1.00 | MET (0.73) | METKITFLT3KDREGFR | |
| SCHEMBL29693479 | 1.00 | MET (0.73) | METKITFLT3KDREGFR | |
| SCHEMBL3832582 | 0.94 | MET (0.70) | METKITFLT3KDREGFR | |
| SCHEMBL4410650 | 0.93 | MET (0.69) | METKITFLT3KDREGFR | |
| SCHEMBL22566439 | 0.93 | MET (0.71) | METKITFLT3KDREGFR | |
| SCHEMBL371863 | 0.93 | MET (0.71) | METKITFLT3KDREGFR | |
| SCHEMBL22553045 | 0.93 | MET (0.84) | METKITFLT3KDREGFR | |
| SCHEMBL371769 | 0.93 | MET (0.71) | METKITFLT3KDREGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200331860-A1 | C-Met Modulators and Methods of Use | EXELIXIS INC (US) | 2020-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200331860-A1 | C-Met Modulators and Methods of Use | FLT4, FLT1, MET | MET 3/4885KIT 5/4885FLT3 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.