SCHEMBL22566464

SCHEMBL22566464

C=CC(=O)Oc1ccc(-c2ccc(OCc3ccc(-c4ccc(OC(=O)C(=C)C)cc4)cc3)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.50
FFAR1 O14842 2/20 0.43
MAOB P27338 6/20 0.43
ELANE P08246 1/20 0.43
MAOA P21397 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.40
ALDH1A1 P00352 1/20 0.40
HTT P42858 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
KMT2A Q03164 1/20 0.40
ATM Q13315 1/20 0.40
PARP10 Q53GL7 1/20 0.40
NPC1 O15118 1/20 0.40
POLB P06746 1/20 0.40
RAB9A P51151 1/20 0.40
RXRA P19793 1/20 0.40
RXRB P28702 1/20 0.40
ALOX5 P09917 1/20 0.39
PTGS1 P23219 1/20 0.39
PTGS2 P35354 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26362237 1.00 THRB (0.50) THRBFFAR1MAOBELANEMAOA
SCHEMBL22566506 1.00 THRB (0.50) THRBFFAR1MAOBELANEMAOA
SCHEMBL26362365 1.00 THRB (0.50) THRBFFAR1MAOBELANEMAOA
SCHEMBL26362248 1.00 THRB (0.50) THRBFFAR1MAOBELANEMAOA
SCHEMBL22566608 1.00 THRB (0.50) THRBFFAR1MAOBELANEMAOA
SCHEMBL26362173 0.96 THRB (0.54) THRBFFAR1MAOBELANEMAOA
SCHEMBL26362171 0.96 THRB (0.54) THRBFFAR1MAOBELANEMAOA
SCHEMBL22596640 0.92 MAOB (0.49) FFAR1MAOBELANEMAOASMN1; SMN2
SCHEMBL22596477 0.92 MAOB (0.49) FFAR1MAOBELANEMAOASMN1; SMN2
SCHEMBL26362251 0.92 MAOB (0.49) FFAR1MAOBELANEMAOASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11773327-B2 PSA-type liquid crystal composition and display device having same JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-10-03 US disclosed
US-11773327-B2 PSA-type liquid crystal composition and display device having same JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-10-03 US disclosed
US-20200332195-A1 PSA-TYPE LIQUID CRYSTAL COMPOSITION AND DISPLAY DEVICE HAVING SAME JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2020-10-22 US disclosed