SCHEMBL22566483

SCHEMBL22566483

C=CC(=O)Oc1ccc(-c2ccc(-c3ccc(CCOC(=O)C(=C)C)cc3)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 4/20 0.57
POLB P06746 1/20 0.41
APEX1 P27695 1/20 0.41
HTT P42858 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
ACACB O00763 1/20 0.37
ACACA Q13085 1/20 0.37
ELANE P08246 1/20 0.37
PDE6D O43924 1/20 0.37
NPC1 O15118 1/20 0.36
MAPT P10636 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CA1 P00915 2/20 0.35
CA12 O43570 1/20 0.35
MET P08581 1/20 0.35
CA4 P22748 1/20 0.35
CA6 P23280 1/20 0.35
CA5A P35218 1/20 0.35
CA7 P43166 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26362183 1.00 THRB (0.57) THRBPOLBAPEX1HTTTDP1
SCHEMBL22566603 0.93 THRB (0.50) THRBPOLBAPEX1HTTTDP1
SCHEMBL22566482 0.93 THRB (0.50) THRBPOLBAPEX1HTTTDP1
SCHEMBL22600437 0.92 THRB (0.58) THRBPOLBAPEX1HTTTDP1
SCHEMBL26362281 0.91 THRB (0.52) THRBPOLBAPEX1HTTTDP1
SCHEMBL18194805 0.91 THRB (0.52) THRBPOLBAPEX1HTTTDP1
SCHEMBL12092909 0.89 ELANE (0.47) THRBPOLBAPEX1HTTTDP1
SCHEMBL690155 0.89 ELANE (0.47) THRBPOLBAPEX1HTTTDP1
SCHEMBL17433312 0.89 THRB (0.53) THRBPOLBAPEX1HTTTDP1
SCHEMBL17461526 0.88 THRB (0.50) THRBPOLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11773327-B2 PSA-type liquid crystal composition and display device having same JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-10-03 US disclosed
US-11773327-B2 PSA-type liquid crystal composition and display device having same JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-10-03 US disclosed
US-20200332195-A1 PSA-TYPE LIQUID CRYSTAL COMPOSITION AND DISPLAY DEVICE HAVING SAME JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2020-10-22 US disclosed