Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NT5E | P21589 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL22559646 | 0.99 | KDM4E (0.52) | KDM4ENPC1L3MBTL1ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL29394980 | 0.99 | KDM4E (0.52) | KDM4ENPC1L3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL22567102 | 0.88 | ALDH1A1 (0.51) | KDM4ENPC1L3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL8605903 | 0.83 | NPC1 (0.76) | KDM4ENPC1L3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL241393 | 0.81 | IDO1 (0.54) | KDM4ENPC1L3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL22559669 | 0.77 | ALDH1A1 (0.56) | KDM4EL3MBTL1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL19848719 | 0.76 | KDM4E (0.53) | KDM4ENPC1L3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL19848336 | 0.75 | NPC1 (0.55) | KDM4ENPC1L3MBTL1ALDH1A1GAA | |
| SCHEMBL2627246 | 0.75 | KDM4E (0.64) | KDM4ENPC1L3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL22559642 | 0.73 | KHK (0.65) | KDM4ENPC1ALDH1A1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020215022-A1 | NOVEL COMPOUNDS AND METHODS OF USE TREATING FRUCTOSE-RELATED DISORDERS OR DISEASES | COLORADO RESEARCH PARTNERS, LLC (US) | 2020-10-22 | — | — | WO | disclosed |