Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 14/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 12/20 | 0.36 |
| ▸ | ITK | Q08881 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15565197 | 0.86 | SLC6A2 (0.49) | SLC6A2SLC6A4HTR2AHRH1SLC6A3 | |
| SCHEMBL15564380 | 0.83 | ITK (0.45) | KLKB1ITKALDH1A1MAPTPKM | |
| SCHEMBL15565762 | 0.83 | ITK (0.45) | KLKB1ITKALDH1A1MAPTPKM | |
| SCHEMBL22557273 | 0.82 | KLKB1 (0.44) | KLKB1ITKCYP2D6 | |
| SCHEMBL15564620 | 0.81 | KLKB1 (0.36) | KLKB1ITKALDH1A1MAPTPKM | |
| SCHEMBL16786480 | 0.81 | OPRM1 (0.42) | KLKB1SLC6A2ITKALDH1A1MAPT | |
| SCHEMBL15565480 | 0.79 | HTR2A (0.43) | KLKB1SLC6A2SLC6A4ITKHTR2A | |
| Hydrochloric Acid SCHEMBL17822228 | 0.78 | TDP1 (0.45) | KLKB1SLC6A2SLC6A4ITKHTR2A | |
| SCHEMBL15564560 | 0.77 | ITK (0.45) | KLKB1SLC6A2ITKALDH1A1MAPT | |
| SCHEMBL15564175 | 0.77 | HTR2A (0.46) | KLKB1SLC6A2SLC6A4ITKHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020212697-A1 | INHIBITOR COMPOUNDS | Azeria Therapeutics Limited (GB) | 2020-10-22 | — | — | WO | disclosed |