⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7707964 | 0.97 | — | — | |
| Water SCHEMBL7712021 | 0.94 | TSHR (0.30) | — | |
| SCHEMBL6122897 | 0.74 | ALDH1A1 (0.47) | — | |
| SCHEMBL27658451 | 0.74 | — | — | |
| SCHEMBL6122892 | 0.74 | ALDH1A1 (0.47) | — | |
| SCHEMBL5950718 | 0.69 | — | — | |
| SCHEMBL5950720 | 0.69 | — | — | |
| SCHEMBL28886659 | 0.69 | — | — | |
| SCHEMBL11184949 | 0.69 | — | — | |
| SCHEMBL251832 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112390722-A | Continuous flow process for amine alkylation reaction | 浙江瑞博制药有限公司 | 2021-02-23 | — | — | CN | claimed |
| US-20260098047-A1 | Anti-Giardial Compounds | COMMW SCIENT IND RES ORG (AU) | 2026-04-09 | — | — | US | disclosed |
| WO-2024011294-A1 | ANTI-GIARDIAL COMPOUNDS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2024-01-18 | — | — | WO | disclosed |
| US-20220372061-A1 | NOVEL NUCLEOTIDE ANALOGUES AND METHODS FOR USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-11-24 | — | — | US | disclosed |
| EP-3997101-A1 | NOVEL NUCLEOTIDE ANALOGUES AND METHODS FOR USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-05-18 | — | — | EP | disclosed |
| CN-112390722-A | Continuous flow process for amine alkylation reaction | 浙江瑞博制药有限公司 | 2021-02-23 | — | — | CN | disclosed |
| CN-112390722-A | Continuous flow process for amine alkylation reaction | 浙江瑞博制药有限公司 | 2021-02-23 | — | — | CN | disclosed |
| WO-2021007458-A1 | NOVEL NUCLEOTIDE ANALOGUES AND METHODS FOR USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2021-01-14 | — | — | WO | disclosed |
| WO-2020260004-A1 | RADIATION CURABLE INKJET INK FOR ALKALINE ETCHING OR PLATING APPLICATIONS | AGFA-GEVAERT NV (BE) | 2020-12-30 | — | — | WO | disclosed |
| CN-110776479-A | Thiazine-like compounds, preparation method and application thereof | 盖斯特里希医药公司 | 2020-02-11 | — | — | CN | disclosed |
| EP-0960092-A1 | METHOD FOR THE PREPARATION OF ALPHA-CHLORINATED CHLOROFORMATES | PPG Industries Ohio, Inc. (US) | 1999-12-01 | — | — | EP | disclosed |
| WO-1999054272-A1 | PROCESS FOR THE PREPARATION OF 2-HYDROXYALKYL HALOPHENONES | AVECIA LIMITED (GB) | 1999-10-28 | — | — | WO | disclosed |
| WO-1999015503-A2 | PROCESS FOR MAKING DIARYL PYRIDINES USEFUL AS COX-2 INHIBITORS | MERCK & CO., INC. (US) | 1999-04-01 | — | — | WO | disclosed |
| US-5861419-A | ANTIINFLAMMATORY AGENTS; ANTIPYRETICS, ANALGESICS; ETORICOXIB PATENT | MERCK FROSST CANAD, INC. (CA) | 1999-01-19 | — | — | US | disclosed |
| WO-1998047871-A1 | PROCESS FOR MAKING 2-ARYL-3-ARYL-5-HALO PYRIDINES USEFUL AS COX-2 INHIBITORS | MERCK & CO., INC. (US) | 1998-10-29 | — | — | WO | disclosed |
| WO-1998030533-A1 | METHOD FOR THE PREPARATION OF ALPHA-CHLORINATED CHLOROFORMATES | PPG INDUSTRIES OHIO, INC. (US) | 1998-07-16 | — | — | WO | disclosed |
| US-5712407-A | Method for the preparation of alpha-chlorinated chloroformates | PPG INDUSTRIES, INC. (US) | 1998-01-27 | — | — | US | disclosed |
| EP-0189774-B1 | PROCESS FOR PRODUCTION OF N,N-DISUBSTITUTED CARBOXYLIC ACID AMIDES | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1989-04-12 | — | — | EP | disclosed |
| EP-0189774-A1 | Process for production of N,N-disubstituted carboxylic acid amides | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1986-08-06 | — | — | EP | disclosed |
| US-4225719-A | Process for preparing 2-amino-5-formylthiazole and its hydrobromide salt | EASTMAN KODAK COMPANY (US) | 1980-09-30 | — | — | US | disclosed |