Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15084444 | 1.00 | LMNA (0.56) | LMNAPTPN1CDC25BL3MBTL1CYP3A4 | |
| SCHEMBL18236136 | 0.86 | LMNA (0.44) | LMNAPTPN1CDC25BCYP3A4TSHR | |
| SCHEMBL19979028 | 0.85 | CYP3A4 (0.40) | LMNACYP3A4TSHRMAPT | |
| SCHEMBL22569893 | 0.82 | LMNA (0.56) | LMNAPTPN1CDC25BL3MBTL1TSHR | |
| SCHEMBL22579751 | 0.82 | LMNA (0.56) | LMNAPTPN1CDC25BL3MBTL1TSHR | |
| SCHEMBL22579610 | 0.82 | LMNA (0.56) | LMNAPTPN1CDC25BL3MBTL1TSHR | |
| SCHEMBL20404071 | 0.82 | LMNA (0.56) | LMNAPTPN1CDC25BL3MBTL1TSHR | |
| SCHEMBL435272 | 0.82 | LMNA (0.56) | LMNAPTPN1CDC25BL3MBTL1TSHR | |
| SCHEMBL524084 | 0.81 | LMNA (0.58) | LMNAPTPN1CDC25BL3MBTL1TSHR | |
| SCHEMBL28102964 | 0.81 | LMNA (0.58) | LMNAPTPN1CDC25BL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020210970-A1 | IMIDAZOTRIAZINE DERIVATIVES AS CD73 INHIBITORS | BIOARDIS LLC (US) | 2020-10-22 | — | — | WO | disclosed |