Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CCNC | P24863 | 2/20 | 0.36 |
| ▸ | CDK8 | P49336 | 2/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 4/20 | 0.35 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | CD38 | P28907 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.34 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.34 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22553750 | 0.83 | CYP11B2 (0.39) | CYP11B2NPC1CCNCCDK8CHEK1 | |
| SCHEMBL22553742 | 0.76 | CYP11B2 (0.40) | CYP11B2NPC1CCNCCDK8PIP4K2A | |
| SCHEMBL30730827 | 0.76 | CYP11B2 (0.40) | CYP11B2NPC1CCNCCDK8PIP4K2A | |
| SCHEMBL30730847 | 0.76 | PIP4K2A (0.40) | CYP11B2NPC1CCNCCDK8PIP4K2A | |
| SCHEMBL22553771 | 0.76 | PIP4K2A (0.40) | CYP11B2NPC1CCNCCDK8PIP4K2A | |
| SCHEMBL22553945 | 0.75 | PIP4K2A (0.55) | CYP11B2NPC1CCNCCDK8CHEK1 | |
| SCHEMBL30730807 | 0.75 | PIP4K2A (0.55) | CYP11B2NPC1CCNCCDK8CHEK1 | |
| SCHEMBL22554234 | 0.74 | CCNC (0.41) | CYP11B2NPC1CCNCCDK8CHEK1 | |
| SCHEMBL22554028 | 0.74 | MEN1 (0.40) | CYP11B2NPC1CCNCCDK8PIP4K2A | |
| SCHEMBL30731000 | 0.74 | MEN1 (0.40) | CYP11B2NPC1CCNCCDK8PIP4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200331913-A1 | ARYL-BIPYRIDINE AMINE DERIVATIVES AS PHOSPHATIDYLINOSITOL PHOSPHATE KINASE INHIBITORS | HIBERCELL, INC. | 2020-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200331913-A1 | ARYL-BIPYRIDINE AMINE DERIVATIVES AS PHOSPHATIDYLINOSITOL PHOSPHATE KINASE INHIBITORS | PIP5K1A, PIP5K1B, PIP5K1C | CYP11B2 3643/4885NPC1 1648/4885CCNC 2067/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.