Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.31 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22569896 | 0.90 | TNK2 (0.31) | HRH4HRH3TNK2 | |
| SCHEMBL23278048 | 0.87 | TNK2 (0.33) | HRH4HRH3TNK2 | |
| SCHEMBL17106669 | 0.85 | PTPN1 (0.34) | — | |
| SCHEMBL19412708 | 0.85 | PTPN1 (0.34) | — | |
| SCHEMBL24557910 | 0.83 | PDE2A (0.34) | — | |
| SCHEMBL22569956 | 0.82 | HRH4 (0.32) | HRH4HRH3TNK2 | |
| SCHEMBL12835934 | 0.79 | HRH4 (0.33) | HRH4HRH3 | |
| SCHEMBL12243125 | 0.79 | HRH4 (0.33) | HRH4HRH3 | |
| SCHEMBL23823026 | 0.78 | TNK2 (0.34) | HRH4HRH3TNK2 | |
| SCHEMBL17131351 | 0.78 | TSHR (0.31) | TNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020211672-A1 | CD73 INHIBITORS | BIOARDIS LLC (US) | 2020-10-22 | — | — | WO | disclosed |