Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 20/20 | 0.64 |
| ▸ | CCND1 | P24385 | 20/20 | 0.64 |
| ▸ | CCND3 | P30281 | 20/20 | 0.64 |
| ▸ | CDK6 | Q00534 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22553513 | 0.87 | CDK4 (0.77) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL22585850 | 0.87 | CDK4 (0.78) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL22553603 | 0.87 | CDK4 (0.78) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL22585440 | 0.87 | CDK4 (0.78) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL22553607 | 0.87 | CDK4 (0.78) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL22553580 | 0.82 | CDK4 (0.81) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL22553543 | 0.82 | CDK4 (0.81) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL22585506 | 0.82 | CDK4 (0.81) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL22553610 | 0.82 | CDK4 (0.79) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL22585442 | 0.82 | CDK4 (0.79) | CDK4CCND1CCND3CDK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020212865-A1 | ANTI-PROLIFERATIVE AGENTS FOR TREATING PAH | PFIZER INC. (US) | 2020-10-22 | — | — | WO | disclosed |