SCHEMBL22587980

SCHEMBL22587980

COc1ccc(Oc2c(-c3cn(C)c(=O)c4[nH]ccc34)ccn(C)c2=O)cc1

nearest known ligand 0.58

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ BRD4 O60885 20/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22587728 0.89 BRD4 (0.57) BRD4
SCHEMBL22588209 0.89 BRD4 (0.72) BRD4
SCHEMBL22588319 0.89 BRD4 (0.56) BRD4
SCHEMBL24397918 0.84 BRD4 (0.58) BRD4
SCHEMBL22588343 0.84 BRD4 (0.64) BRD4
SCHEMBL31589682 0.82 BRD4 (0.70) BRD4
SCHEMBL24397937 0.81 BRD4 (0.57) BRD4
SCHEMBL22588455 0.81 BRD4 (0.55) BRD4
SCHEMBL24398044 0.81 BRD4 (0.55) BRD4
SCHEMBL22588375 0.81 BRD4 (0.61) BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12384777-B2 Compounds comprising N-methyl-2-pyridone, and pharmaceutically acceptable salts Tay Therapeutics Limited (GB) 2025-08-12 — — US disclosed
US-20220204500-A1 COMPOUNDS COMPRISING N-METHYL-2-PYRIDONE, AND PHARMACEUTICALLY ACCEPTABLE SALTS UNIVERSITY OF DUNDEE (GB) 2022-06-30 — — US disclosed
US-20220204500-A1 COMPOUNDS COMPRISING N-METHYL-2-PYRIDONE, AND PHARMACEUTICALLY ACCEPTABLE SALTS UNIVERSITY OF DUNDEE (GB) 2022-06-30 — — US disclosed
CN-113924298-A Compounds comprising N-methyl-2-pyridone and pharmaceutically acceptable salts 邓迪大学 2022-01-11 — — CN disclosed
WO-2020216779-A1 COMPOUNDS COMPRISING N-METHYL-2-PYRIDONE, AND PHARMACEUTICALLY ACCEPTABLE SALTS UNIVERSITY OF DUNDEE (GB) 2020-10-29 — — WO disclosed
WO-2020216779-A1 COMPOUNDS COMPRISING N-METHYL-2-PYRIDONE, AND PHARMACEUTICALLY ACCEPTABLE SALTS UNIVERSITY OF DUNDEE (GB) 2020-10-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220204500-A1 COMPOUNDS COMPRISING N-METHYL-2-PYRIDONE, AND PHARMACEUTICALLY ACCEPTABLE SALTS TPMT, IL5, P2RY6 BRD4 303/4885
US-12384777-B2 Compounds comprising N-methyl-2-pyridone, and pharmaceutically acceptable salts TPMT, IL5, P2RY6 BRD4 303/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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