Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 19/20 | 0.55 |
| ▸ | TAF1 | P21675 | 2/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.47 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.47 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.47 |
| ▸ | EP300 | Q09472 | 1/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.47 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.47 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.47 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29564851 | 0.92 | BRD4 (0.52) | BRD4TAF1TRIM24SMARCA2SMARCA4 | |
| SCHEMBL24397906 | 0.89 | BRD4 (0.49) | BRD4 | |
| SCHEMBL24397989 | 0.89 | BRD4 (0.49) | BRD4 | |
| SCHEMBL24397953 | 0.88 | BRD4 (0.48) | BRD4 | |
| SCHEMBL22588381 | 0.87 | BRD4 (0.52) | BRD4 | |
| SCHEMBL24398016 | 0.87 | BRD4 (0.52) | BRD4TAF1BRD9 | |
| SCHEMBL29564688 | 0.87 | BRD4 (0.54) | BRD4 | |
| SCHEMBL24397887 | 0.86 | CECR2 (0.48) | BRD4TAF1CECR2BRD9 | |
| SCHEMBL24397918 | 0.86 | BRD4 (0.58) | BRD4 | |
| SCHEMBL24398081 | 0.86 | BRD4 (0.46) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022090699-A1 | PYRIDONE-CONTAINING COMPOUNDS AS BROMODOMAIN PROTEIN INHIBITORS | In4Derm Limited (GB) | 2022-05-05 | — | — | WO | disclosed |
| WO-2022090699-A1 | PYRIDONE-CONTAINING COMPOUNDS AS BROMODOMAIN PROTEIN INHIBITORS | In4Derm Limited (GB) | 2022-05-05 | — | — | WO | disclosed |