Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | ECE2 | P0DPD6 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31285878 | 1.00 | MAPK1 (0.48) | MAPK1HDAC3CCR3ECE2MAPT | |
| SCHEMBL22605517 | 0.85 | HDAC3 (0.60) | HDAC3CCR3ECE2CCNE1CDK2 | |
| SCHEMBL31285852 | 0.85 | HDAC3 (0.60) | HDAC3CCR3ECE2CCNE1CDK2 | |
| SCHEMBL28527229 | 0.84 | SYK (0.41) | CCR3ECE2SYKTRPV1 | |
| SCHEMBL30317154 | 0.83 | HDAC3 (0.48) | HDAC3CCR3ECE2ALDH1A1CCNE1 | |
| SCHEMBL22605817 | 0.82 | HDAC3 (0.52) | HDAC3CCR3ECE2MAPTALDH1A1 | |
| SCHEMBL28527704 | 0.79 | MAPK1 (0.53) | MAPK1MAPTPKMRAB9AALDH1A1 | |
| SCHEMBL31285863 | 0.78 | MAPK1 (0.56) | MAPK1ALDH1A1SIGMAR1NPSR1 | |
| SCHEMBL22605881 | 0.78 | MAPK1 (0.53) | MAPK1MAPTPKMRAB9AALDH1A1 | |
| SCHEMBL22587877 | 0.78 | MAPK1 (0.56) | MAPK1ALDH1A1SIGMAR1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230099441-A1 | HETEROCYCLIC COMPOUND, APPLICATION THEREOF, AND COMPOSITION CONTAINING SAME | GENEROS BIOPHARMA LTD. (CN) | 2023-03-30 | — | — | US | disclosed |
| WO-2020216378-A1 | HETEROCYCLIC COMPOUND, APPLICATION THEREOF, AND COMPOSITION CONTAINING SAME | 健艾仕生物医药有限公司 | 2020-10-29 | — | — | WO | disclosed |
| WO-2020216378-A1 | HETEROCYCLIC COMPOUND, APPLICATION THEREOF, AND COMPOSITION CONTAINING SAME | 健艾仕生物医药有限公司 | 2020-10-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230099441-A1 | HETEROCYCLIC COMPOUND, APPLICATION THEREOF, AND COMPOSITION CONTAINING SAME | STAT5A, STAT5B, JAK2 | MAPK1 258/4885HDAC3 43/4885CCR3 1931/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.