Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PANK3 | Q9H999 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22605881 | 0.86 | MAPK1 (0.53) | MAPK1ALDH1A1LMNAKDM4ERECQL | |
| SCHEMBL22587877 | 0.84 | MAPK1 (0.56) | MAPK1HRH3ALDH1A1LMNAKDM4E | |
| SCHEMBL31285863 | 0.84 | MAPK1 (0.56) | MAPK1HRH3ALDH1A1LMNAKDM4E | |
| SCHEMBL22605502 | 0.83 | HRH3 (0.51) | HRH3ALDH1A1KDM4EPANK3MAPT | |
| SCHEMBL22587986 | 0.79 | MAPK1 (0.48) | MAPK1ALDH1A1TRPV1MAPTPKM | |
| SCHEMBL31285878 | 0.79 | MAPK1 (0.48) | MAPK1ALDH1A1TRPV1MAPTPKM | |
| SCHEMBL16407599 | 0.78 | MAPK1 (0.60) | MAPK1ALDH1A1LMNAMAPTPKM | |
| SCHEMBL3992139 | 0.77 | MAPK1 (0.65) | MAPK1ALDH1A1MAPTPKMRAB9A | |
| SCHEMBL3992132 | 0.77 | MAPK1 (0.65) | MAPK1ALDH1A1MAPTPKMRAB9A | |
| SCHEMBL4910166 | 0.76 | LMNA (0.63) | MAPK1ALDH1A1LMNAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848598-B | Heterocyclic compound, application thereof and composition containing same | 健艾仕生物医药有限公司 | 2024-12-10 | — | — | CN | disclosed |
| CN-111848598-A | Heterocyclic ring-containing compound, application thereof and composition containing heterocyclic ring-containing compound | 健艾仕生物医药有限公司 | 2020-10-30 | — | — | CN | disclosed |