Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.58 |
| ▸ | HKDC1 | Q2TB90 | 5/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22589793 | 1.00 | HSP90AA1 (0.58) | HSP90AA1HKDC1MITFDUSP3PTPN11 | |
| SCHEMBL22589664 | 0.88 | HSP90AA1 (0.65) | HSP90AA1HKDC1MITFALDH1A1HTT | |
| SCHEMBL22589663 | 0.88 | HSP90AA1 (0.65) | HSP90AA1HKDC1MITFALDH1A1HTT | |
| SCHEMBL22589679 | 0.82 | TOP2A (0.38) | HSP90AA1HKDC1TOP2AKDM4EALDH1A1 | |
| SCHEMBL24512426 | 0.80 | HSP90AA1 (0.46) | HSP90AA1HKDC1TOP2AKDM4EALDH1A1 | |
| SCHEMBL22589662 | 0.80 | HSP90AA1 (0.38) | HSP90AA1HKDC1TOP2AKDM4EALDH1A1 | |
| SCHEMBL29743153 | 0.80 | HSP90AA1 (0.46) | HSP90AA1HKDC1TOP2AKDM4EALDH1A1 | |
| SCHEMBL17975297 | 0.77 | HSP90AA1 (0.65) | HSP90AA1HKDC1MITFDUSP3PTPN11 | |
| SCHEMBL9321800 | 0.74 | HSP90AA1 (1.00) | HSP90AA1HKDC1MITFTOP2AKDM4E | |
| SCHEMBL17975335 | 0.74 | HSP90AA1 (1.00) | HSP90AA1HKDC1MITFTOP2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12344626-B2 | Pharmaceutical compounds and therapeutic methods | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2025-07-01 | — | — | US | disclosed |
| US-20220185827-A1 | PHARMACEUTICAL COMPOUNDS AND THERAPEUTIC METHODS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2022-06-16 | — | — | US | disclosed |
| WO-2020219587-A1 | PHARMACEUTICAL COMPOUNDS AND THERAPEUTIC METHODS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2020-10-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12344626-B2 | Pharmaceutical compounds and therapeutic methods | SLC30A5, SLC39A11, SLC30A7 | HSP90AA1 2676/4885HKDC1 644/4885MITF 1052/4885 |
| US-20220185827-A1 | PHARMACEUTICAL COMPOUNDS AND THERAPEUTIC METHODS | SLC30A5, SLC39A11, SLC30A7 | HSP90AA1 2676/4885HKDC1 644/4885MITF 1052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.