Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29743153 | 1.00 | HSP90AA1 (0.46) | HSP90AA1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL24512361 | 0.87 | HSP90AA1 (0.51) | HSP90AA1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL29743152 | 0.87 | HSP90AA1 (0.51) | HSP90AA1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL22589679 | 0.86 | TOP2A (0.38) | HSP90AA1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL22589662 | 0.84 | HSP90AA1 (0.38) | HSP90AA1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL29489544 | 0.83 | HSP90AA1 (0.44) | HSP90AA1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL29743151 | 0.80 | NPC1 (0.46) | HSP90AA1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL22589793 | 0.80 | HSP90AA1 (0.58) | HSP90AA1ALDH1A1KDM4EOPRK1HKDC1 | |
| SCHEMBL22589794 | 0.80 | HSP90AA1 (0.58) | HSP90AA1ALDH1A1KDM4EOPRK1HKDC1 | |
| SCHEMBL24512360 | 0.73 | HSP90AA1 (0.41) | HSP90AA1ALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220185827-A1 | PHARMACEUTICAL COMPOUNDS AND THERAPEUTIC METHODS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2022-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220185827-A1 | PHARMACEUTICAL COMPOUNDS AND THERAPEUTIC METHODS | SLC30A5, SLC39A11, SLC30A7 | HSP90AA1 2676/4885ALDH1A1 2006/4885MEN1 364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.