Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.61 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30019496 | 0.89 | EGFR (0.52) | EGFR | |
| SCHEMBL22595478 | 0.89 | EGFR (0.52) | EGFR | |
| SCHEMBL22595140 | 0.88 | EGFR (0.63) | EGFR | |
| SCHEMBL23442740 | 0.88 | EGFR (0.53) | EGFRPLK1 | |
| SCHEMBL22025588 | 0.88 | EGFR (0.78) | EGFR | |
| SCHEMBL22595141 | 0.88 | EGFR (0.79) | EGFR | |
| SCHEMBL22595430 | 0.86 | EGFR (0.48) | EGFR | |
| SCHEMBL22595153 | 0.84 | EGFR (0.47) | EGFRPLK1 | |
| SCHEMBL22595805 | 0.84 | EGFR (0.48) | EGFR | |
| Trifluoroacetic Acid SCHEMBL28597344 | 0.83 | EGFR (0.71) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020216371-A1 | EGFR INHIBITOR AND APPLICATION THEREOF | 江苏先声药业有限公司 | 2020-10-29 | — | — | WO | disclosed |